| Active Ingredient: 300 mg of Methaqualone (often combined with diphenhydramine). | |
| Mechanism of Action: It acts as a central nervous system (CNS) depressant, binding to GABAA receptor | |
| Physical Appearance: Historically, it appeared as tablets, often marked with "714" or white/blue cap |
Methaqualone acts primarily as a sedative, reducing anxiety and inducing sleep. It binds to GABAA receptors, where it functions as a positive allosteric modulator at many receptor subtypes, enhancing the inhibitory effects of the neurotransmitter GABA. It shows negligible affinity for a wide array of other potential targets, including other receptors and neurotransmitter transporters. This action is similar to that of benzodiazepines like diazepam
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